Research Associate

Job Description

Under the direction of the Principal Investigator or Designee, the Research Associate performs a variety of complex research experiments.
The Bosco laboratory at the University of Massachusetts Chan Medical School ( has an open position for a Post-Doctoral Fellow. Our laboratory is highly interdisciplinary and collaborative. We are located in the state-of-the-art Albert Sherman Center for translational science at the University Campus in Worcester, MA, which is about 1 hour from both Boston, MA and Providence, RI. Our research focuses on molecular mechanisms underlying neurodegeneration, with a focus on amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our model systems include mouse models and cells (e.g., neurons and microglia) derived from human induced pluripotent stem cells (iPSCs). Our lab also utilizes biochemical and biophysical approaches to understand how disease-causing mutations affect protein structure and function at the molecular level. Members are welcome to work with various models, or to focus on one.
Relevant recent publications from our lab:
Lin, et al, Nature Neuroscience, 2021 (
Schmidt, et al, PNAS, 2021 (
Please visit our website for a list of publications and descriptions of ongoing projects ( Applications from outside the US are welcomed.


• Conducts in-depth analysis of research experiments
• Performs complex laboratory experiments
• Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
• Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
• May modify protocols and be responsible for a single, independent research project
• Assists in writing the text of scientific publications and grants. Reviews literature
• Trains new laboratory personnel, students, and collaborators
• Maintains laboratory supplies and equipment
• Complies with all safety and infection control standards
• Perform other duties as required.

• Bachelor’s degree in Biological Sciences, or equivalent experience
• Knowledge of Microsoft Office products
• Strong ability to analyze complex visual data in a quantitative and objective manner
• Judgment and action skills required to solve commonly encountered problems
• Experience working with molecular biology, including RNA/DNA processing, sterile-culture techniques and/or animal handling.
Under the direction of the Principal Investigator, or designee
May functionally supervise Lab Technicians and Aides
Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.

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