Research Associate

Job Description

Overview
POSITION SUMMARY:
Under the direction of the Principal Investigator or Designee, the Research Associate performs a variety of complex research experiments.
The Bosco laboratory at the University of Massachusetts Chan Medical School (www.umassmed.edu/umasschan/) has an open position for a Post-Doctoral Fellow. Our laboratory is highly interdisciplinary and collaborative. We are located in the state-of-the-art Albert Sherman Center for translational science at the University Campus in Worcester, MA, which is about 1 hour from both Boston, MA and Providence, RI. Our research focuses on molecular mechanisms underlying neurodegeneration, with a focus on amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Our model systems include mouse models and cells (e.g., neurons and microglia) derived from human induced pluripotent stem cells (iPSCs). Our lab also utilizes biochemical and biophysical approaches to understand how disease-causing mutations affect protein structure and function at the molecular level. Members are welcome to work with various models, or to focus on one.
Relevant recent publications from our lab:
Lin, et al, Nature Neuroscience, 2021 (pubmed.ncbi.nlm.nih.gov/34059832/)
Schmidt, et al, PNAS, 2021 (pubmed.ncbi.nlm.nih.gov/34074767/)
Please visit our website for a list of publications and descriptions of ongoing projects (www.boscolab.com/). Applications from outside the US are welcomed.

Responsibilities

ESSENTIAL FUNCTIONS:
• Conducts in-depth analysis of research experiments
• Performs complex laboratory experiments
• Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
• Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
• May modify protocols and be responsible for a single, independent research project
• Assists in writing the text of scientific publications and grants. Reviews literature
• Trains new laboratory personnel, students, and collaborators
• Maintains laboratory supplies and equipment
• Complies with all safety and infection control standards
• Perform other duties as required.

Qualifications
REQUIRED QUALIFICATIONS:
• Bachelor’s degree in Biological Sciences, or equivalent experience
• Knowledge of Microsoft Office products
• Strong ability to analyze complex visual data in a quantitative and objective manner
• Judgment and action skills required to solve commonly encountered problems
PREFERRED QUALIFICATIONS:
• Experience working with molecular biology, including RNA/DNA processing, sterile-culture techniques and/or animal handling.
SUPERVISION RECEIVED:
Under the direction of the Principal Investigator, or designee
SUPERVISION EXERCISED:
May functionally supervise Lab Technicians and Aides
ENVIRONMENTAL WORKING CONDITIONS:
Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens.

Apply Here: www.click2apply.net/j7POOPiVVjl7ZTwdYUJzgX

PI171309708